Wales centre Jamie Roberts insists his side are doing everything they can to overcome their southern hemisphere hoodoo ahead of the autumn internationals.
Roberts, who scored two tries in the RBS 6 Nations earlier this year, was in the Wales starting XV the last time they beat one of the 'big three' southern hemisphere sides, back in November 2008.
Wales triumphed 21-18 over Australia that day, although the 27-year-old may not have the fondest memories of the game - sustaining a fractured skull just two minutes in.
The Red Dragons have suffered nothing but heartbreak against the Wallabies, New Zealand and South Africa since then however - a 31-30 reverse against the Springboks in June, being the latest.
But Roberts is adamant that the result at the Mbombela Stadium will fuel the Welsh fire when all three southern hemisphere sides visit the Millennium Stadium this November.
"South Africa in the summer was so disappointing - losing that second Test in the last minute," he said. "Everyone will be fuming from that, so we'll chuck everything into it.
"It's easy for us to say we'd love to beat two of the big three, and what have you, but we have to be realistic.
"We haven't won against a Southern Hemisphere side since 2008, so it's still a massive target for us. Hopefully the hard work we've put in will be enough for us to win on the day. We'd love to put down a marker."
Seven uncapped players in Rob Howley's RBS 6 Nations squad marks a major shift in Wales' makeup and with Alun Wyn Jones taking on the captaincy, Sam Warburton likely to contend for a spot on the blindside and new contenders for backline spots, we assess the principal shifts.