The Official Online RBS 6 Nations Store is open. The store has everything you need to get behind your team during the RBS 6 Nations, plus the store is now fully stocked with a much wider range of rugby merchandise.
All bar Attwood, who made his debut in 2010, won first caps on England's successful summer tour to Argentina, when the Pumas were beaten 32-3 in Salta and 51-26 in Buenos Aires.
Calum Clark, back row trio Thomas Waldrom, James Haskell and Tom Johnson as well as Jonathan Joseph and David Strettle make way.
Lancaster said: "This was the toughest EPS selection we've had to make with fierce competition for places in every area of the squad after an excellent summer for England players at all levels.
"Twelve current England players were part of a victorious British & Irish Lions tour, eight others won their first caps in Argentina, a number of rested senior players will have benefited from their break and the future looks healthy after our Under-20 side won the Junior World Championship for the first time.
"Christian Wade and Marland Yarde brought their outstanding Aviva Premiership form to the tour, Kyle Eastmond showed the potential he has and by including him in the squad we get a chance to work with him some more as we build towards the QBE Internationals.
“Up front David Attwood adds a physical presence to the second row and in Matt Kvesic and Billy Vunipola we have young back row players who will challenge our more established back row players hard."