England coach Andy Robinson is expecting an RBS 6 Nations baptism of fire when his side face Wales on Saturday.
Confidence is high in the Welsh camp following impressive autumn displays, both in defeat, against New Zealand and South Africa, while a much-changed England side will arrive without injured World Cup stars like Jonny Wilkinson, Mike Tindall, Will Greenwood and Richard Hill.
But Robinson is hoping his new-look side can draw strength from the intimidating atmosphere that they will inevitably face.
"The thing for us is to be inspired by the atmosphere,'' said Robinson, who is confident the team he has selected will be the one which takes the field despite some recent injury niggles.
"It's a great stadium to play in, and this is what you are involved in international rugby for, to be part of games like this one.
"Our preparations have been going well, there is a tremendous belief among the squad. The players that have come in have had a real enthusiasm about the way they've trained, and I think everyone is just looking forward to getting out on the pitch.
Robinson also believes that England's narrow defeat to Australia in November will provide his team with added motivation.
"'If you think the last time we played, we lost to Australia, and I think the guys were hurt by that. It's history, but it is important we start well in this game.''
And perhaps the key weapon in England's entire armoury will be scrum-half Matt Dawson, recalled to win a 66th cap after being demoted from the elite player group earlier this season when his television commitments came before national squad training.
Dawson has seen off challenges, at least for the time being, from England rivals Harry Ellis and Andy Gomarsall, and he earned Robinson's unstinting praise.
"It was vital that we had strong leadership at nine and 10, and I think that's where he (Dawson) is the best in the world in terms of his leadership, organisation and management of the game,'' said Robinson.
"With the exciting talent that we have in our backs, and the power we have in our forwards, it is important to have someone to lead and organise. He is a hugely competitive player, who really has that edge.''
England Under-18 head coach John Fletcher insists his young side will be better for the experience after beating Italy in the bronze final to round out their 2015 Rugby Europe U18 Championship campaign in style.