England coach Andy Robinson faces an anxious weekend as several of his RBS 6 Nations team return to domestic action.
While his Irish and Welsh counterparts - Eddie O'Sullivan and Mike Ruddock - have their players wrapped in cotton wool, 11 of Robinson's line-up that faced France last Sunday will start Premiership games.
Sale Sharks trio Jason Robinson, Mark Cueto and Charlie Hodgson all feature against Leeds on Friday night, with Bath pair Olly Barkley and Danny Grewcock lining up against a Gloucester side on Saturday that includes prop Phil Vickery.
Forwards Graham Rowntree and Martin Corry, meanwhile, start when Leicester host Newcastle on Saturday, with Sunday's clash between Wasps and Northampton featuring Josh Lewsey, Joe Worsley and Steve Thompson.
Of the remaining four players in action from the start against France, only Newcastle centre Jamie Noon and Leicester lock Ben Kay gain complete breaks this weekend.
And it would be totally in keeping with Robinson's luck this season that further injuries occur just a week before England face unbeaten RBS 6 Nations title contenders Ireland in Dublin.
Saracens director of rugby Mark McCall believes Alex Lozowski has only just scratched the surface of his potential after the 23-year-old celebrated his England recognition by scoring a try-double against Bristol.