Ulster duo Matt McCullough and Roger Wilson will make their Ireland debuts against Japan in the first Test in Osaka on Sunday.
Niall O'Donovan's side is a mix of youth and experience and alongside lock McCullough and number eight Wilson will be provincial team-mates David Humphreys, who captains the side, and 21-year-old Tommy Bowe.
Girvan Dempsey, Kevin Maggs, Humphreys, Peter Stringer and Frankie Sheahan provide experience, while Harlequins utility back Gavin Duffy stands in for British & Irish Lions captain Brian O'Driscoll.
Ireland team to play Japan in the first Test in Osaka on Sunday, June 12.
Team: G Dempsey (Leinster); T Bowe (Ulster), G Duffy (Harlequins), K Maggs (Ulster), A Horgan (Munster); D Humphreys (Ulster, capt), P Stringer (Munster); M Horan (Munster), F Sheahan (Munster), S Best (Ulster), L Cullen (Leinster), M McCullough (Ulster), A Quinlan (Munster), J O'Connor (Wasps), R Wilson (Ulster).
Replacements: B Jackman (Connacht), R Corrigan (Leinster), T Hogan (Munster), E Miller (Leinster), K Campbell (Ulster), J Staunton (Wasps), D Quinlan (Leinster).
Peter O'Mahony was named man of the match against England last month
21 April 2017, 7:22pm
Peter O'Mahony's performance in the RBS 6 Nations finale for Ireland against England was crucial to his selection for the British & Irish Lions on Wednesday, Ireland and Lions defence coach Andy Farrell has revealed.