The first game in any tournament will always be a bit tetchy and fraught.
Even though Wales will come with a bit of confidence as Grand Slam champions, it's at Twickenham and everyone knows how hard it is to play there.
England won't be thinking about revenge for the defeat in last season's competition - they're far too professional for that and will just want to think about performance.
Wales can't worry about injuries, because they know they have to play with the cards they're dealt.
From England's point of view, the game will definitely be won in the forwards; they have to create dominance there so their backs can get into the game.
Wales will want their backs attacking the spaces and creating the tries. We saw last season that they were quite prepared to let you score two tries because they'd go out and score three. So it'll be a case of two totally different types of gameplan.
Lawrence Dallaglio's return to the England fold will be only be good for the team, the players and the supporters.
He is a leader of men, a great ball carrier, very hard and aggressive and, most of all, he wants to win.
Dallaglio will also bring a lot of experience, which is one thing Andy Robinson's squad lacks. Last year, England lost games which experience would have won.
It will be interesting to see Dallaglio and Martin Corry work together; they will be the lynchpin of the side and, if they are both fit and raring, things are looking good.
We need to decide who will fill in the outside centre channel and give someone a proper run at it, whether that's James Simpson-Daniel, Jamie Noon, Ollie Smith or even Josh Lewsey. But they need enough games to make a decent fist of the position.
At full-back you've got to be looking at Mark van Gisbergen, who is a very exciting player and has won everything with Wasps.
I think Robinson should pick one or two younger, inexperienced players and give them that game time, even if it's the last 10 or 15 minutes, to blood them on the international scene.
Tom Varndell played against Samoa, touched the ball twice and scored once, so he's got great promise, and Magnus Lund looks the same.
Wales' acting head coach Rob Howley has given Sam Davies and Rory Thornton a boost ahead of the RBS 6 Nations by naming the uncapped Ospreys duo in his largely experienced squad for the Autumn Internationals.