Scotland head to Cardiff determined to prove last weekend's dramatic victory over pre-tournament favourites France was not just a grand one-off.
Frank Hadden's side produced a stunning display at Murrayfield to secure their first home win over France in more than a decade and lift Scottish rugby from the doldrums.
But captain Jason White warned his men that last weekend's victory was only the start - the next big challenge is to reproduce that form on the road, where Scotland have not won in seven RBS 6 Nations outings.
''I'm quite conscious that the last four games have been at home, so to go away is another big test,'' he said.
''The stadium will be going bananas but we just need to do the things we did well against France and if we do that we should be fine.''
Scotland have made two changes. Hooker Scott Lawson has been brought in to shore up the Scottish lineout, while Australian-born centre Ben MacDougall makes his debut after Marcus di Rollo pulled out injured.
In Wales, Scotland face the defending champions desperate to keep their title bid alive after last weekend's 47-13 defeat to England.
Wales are still struggling badly under the weight of injuries but in 18 months since Mike Ruddock took charge they have only once lost back-to-back Tests - to South Africa in the summer and autumn of 2004.
Ruddock has kept faith with the same starting XV and the open, attacking style which earned them such success last year.
''The same 15 players have a chance to dispel the demons of that loss and show what they are really capable of,'' said Ruddock.
''We lost a couple of games in the autumn but showed our fortitude by coming back to beat Australia for the first time in 18 years. We know that when we lose a game we are more than capable of coming back.''
After losing their Under-20s Six Nations crown to England Under-20s in a thrilling final round, France Under-20s lock Tristan Labouteley insists his side will be out for revenge at this year's Junior World Championship.