After opening their campaign with two victories Wales' luck ran out in round three as France left Parc Eirias with a 16-10 victory.
And Hughes and co were unable to get back to winning ways in round four as they were beaten 67-7 by England, the reigning champions running in ten tries in the process.
Wales got on the board in the final minute with a penalty try, converted by replacement Luke Price, but it was no more than a consolation.
Wales still have the chance to end their campaign on a winning note when they host Scotland on Friday night, and Hughes insists anything less will not be acceptable.
"It's a positive this isn't our last game of the campaign," said the Llanelli centre.
"We have a game next week against Scotland which will be an opportunity for us to get some pride and respect back.
"We said after the game we have to be honest with each other and it's a big week of training now leading into a big game.
"It's very disappointing and I think we were dealt some harsh lessons in terms of how to play international rugby.
"We weren't there at all and not taking anything away from England, I thought they played very well. At times, their play was something we couldn't handle."