Ireland had burst into an early lead, as Jonathan Sexton converted his own try, but Italy got themselves back level when Leonardo Sarto dotted down, Luciano Orquera adding the extras.
However, that was as good as it got for the Italians as their hosts added another fives scores - Sexton helping himself to another try and Andrew Trimble, Cian Healy, Sean Cronin, Fergus McFadden and Jack McGrath all getting in on the act.
And Italy captain Bortolami was adamant a lack of accuracy and ability to keep hold of the ball was their downfall at the Aviva Stadium.
"It was frustrating because we played a poor 80 minutes," the veteran lock said. "We knew the referee would be strict at the breakdown.
"Another frustrating point was we stole many balls but then lost it again. We struggled around the scrum and lineout to get possession.
"I said details are crucial. We lost the first scrum and the second. They were exploiting space throughout the phases and eventually it was too much and we ran out of energy in the second half.
"That's when Ireland started to find space out wide because our defence was tired."