France's 27-6 defeat to Wales last time out has left Les Bleus as one of four teams tied on four points at the top of the table.
Only Scotland, their next opponents this weekend, and winless Italy find themselves out of contention in what is shaping up to be an exciting climax to this year's competition.
France will have to make do without hooker Dimitri Szarzewski for the trip to Murrayfield however after the 31-year-old, who has appeared in all three games so far, picked up an ankle injury playing for club side Racing Metro over the weekend.
He is replaced in the squad by 18-times capped Guilhem Guirado, with France seeking their first away victory in two years.
And while their first defeat of the competition against Wales came as something of a set back, Saint Andre remains confident his side can hold their nerve to claim the title.
"First and foremost we're going to concentrate on the next match and try to give ourselves a (title) final at the Stade de France against Ireland," he said.
"We have two matches of a very high level to come and we must do everything we can to win the Six Nations, starting with a massive performance in Scotland."