Glasgow Warriors have announced that chief executive Ian Riddoch has left the Magners League club.
The departure follows a review of the SRU's commercial activities and leaves the governing body seeking a replacement less than two weeks before the season starts.
Riddoch believes he leaves the club in a healthy position.
He said: "I have had a fantastic two years leading the Warriors and would like to thank all the players, coaches, staff and supporters for their help and support they gave me during that time.
"The Warriors now have a long-term playing venue at Firhill and will shortly move into their new world-class training facilities at Scotstoun.
"This will provide the necessary consistency and facilities the club needs to continue its progress and challenge the leading rugby teams in Europe both on and off the field.
"The last two years have been all about building strong community foundations to ensure that the Warriors are ideally placed to flourish in Glasgow.
"There are strong signs from the schools, grassroots rugby clubs, the media, the business community and the public that the Warriors will continue to go from strength to strength.
"I would like to offer special thanks to all involved at Glasgow Warriors including Sean Lineen for making my time there very special.
"Now that all these plans are in place and moving forward I feel it is the right time to take on a new challenge to further my career however, although I am moving on, I hope to be able to get to Warriors games when I can as the best is yet to come from the squad of players that has been assembled."
SRU chief executive Gordon McKie added: "We have recently reviewed all commercial and marketing activities within Scottish Rugby and have concluded that a new structure is needed to better co-ordinate the selling of all relevant commercial inventories across the organisation.
"To this end, a new head of commercial will be appointed to lead the commercial team who in turn will be responsible for selling all commercial inventories across the organisation.
"I'd like to thank Ian Riddoch for his contributions to Glasgow Warriors over the last two years and we wish him well in the future.
"We plan to appoint Ian's successor in due course."
The 2017 RBS 6 Nations was watched by record numbers of fans
29 March 2017, 12:25pm
After an enthralling RBS 6 Nations Championship of twists, turns, and no small amount of drama on the last day, figures show the RBS 6 Nations is going from strength to strength, year on year, with no sign of slowing down.