Wales coach Warren Gatland will have access to his Grand Slam winners for 13 days before their opener against Scotland at Murrayfield on 8 February after achieving player access he wanted for the RBS 6 Nations.
The major boost to Wales' hopes of retaining the Six Nations title comes after an agreement between the Welsh Rugby Union and the Welsh regions.
Wales also have first call on the players for the entire competition, even though there are two weekends of regional matches during the tournament.
The regions agreed to the terms after meetings at the start of this week.
Italy Under-20s held off a late Samoa blitz to retain their place in the World Rugby U20 Championship on Saturday and head coach Alessandro Troncon believes the experience will have served as a valuable lesson for his young troops.