But Edwards can take some solace from the fact that in finishing fourth, courtesy of victories over Italy and Scotland, Wales booked their place for next summer's World Cup in France.
"It's gutting to lose in the way we did, we knew England were there for the taking," said Edwards.
"To be in the position of winning the game when we haven't got a point against them in the last two years so it was a great opportunity.
"But just like against Ireland, a missed tackle in the last couple of minutes and they score a try that wins the game.
"On the plus side we have qualified for the World Cup so we have 18 months to build towards that. We are in a good position as we've got a young side with plenty of potential and we've shown this season what we are capable of doing."