There are numerous new faces in the 22-man Argentina squad to face Ireland in the first Test on May 26.
Saracens back Tomas de Vedia, Biarritz prop Gaston de Robertis and CASI lock James Stuart are among the uncapped men on duty for the match at Santa Fe.
There are nine players from English and Scottish clubs, including Leeds lock Pablo Bouza.
The countries, who clash in a World Cup group game in September, meet in the second Test in Buenos Aires on 2 June.
Argentina squad - forwards: M Ayerza, P Bouza, G de Robertis, M Durand, J M Fernandez Lobbe, G Fessia, P Gambarini, S Gonzalez Bonorino, J Leguizamon, E Lozada, J Stuart, A Basualdo.
Backs: M Avramovic, F Contepomi, T de Vedia, J Miranda, F Leonelli, L Fleming, H Senillosa, F Serra, B Stortoni, N Vergallo.
England flanker James Haskell insists he will be pushing as hard as possible to be back from a toe injury in time to make his case for a spot in Eddie Jones' side looking to defend their RBS 6 Nations title next year.