France head coach Bernard Laporte has included four uncapped players in his 40-man squad for the RBS 6 Nations Championship, which begins next month.
Front-row forwards Benoit August and Laurent Emmanuelli, centre Romain Cabannes and full-back Anthony Floch have been called up by Les Bleus for the first time.
Laporte has also brought five players - Clement Poitrenaud, Nicolas Mas, Jean-Baptiste Poux, Sebastien Chabal and Sebastien Bruno - back into the squad after spells out of the international reckoning.
The displays of Chabal and Bruno in Sale's recent Heineken Cup games against Stade Francais proved decisive in earning their recalls.
Fly-half Benjamin Boyet and Thomas Castaignede are currently injured but are still named in the group.
There is no place for in-form Stade Francais fly-half Lionel Beauxis, who loses out to fellow number 10 and club colleague David Skrela, while full-backs Julien Laharrague and Pepito Elhorga are dropped after poor showings in the November Tests.
Cabannes, who has been in good form for Biarritz this season, gets the nod over Stade Francais centre Geoffrey Messina in midfield.
Toulouse lock Fabien Pelous, who is recovering from an injury sustained against Llanelli Scarlets in the Heineken Cup last month, will captain the team.
France's first match of the tournament is against Italy in Rome on February 3.
The reigning champions will then travel to Ireland on February 11, in what will be a match-up of Europe's current heavyweights.
Laporte will use the Six Nations to gauge the form of his players ahead of the World Cup, which begins in September and is being played on French soil.
The Les Bleus coach said recently that every member of his 40-man squad will play at least one game in the Six Nations, and that no player will feature in all five matches.
As head coach Stuart Lancaster polishes the axe he will soon wield over his World Cup training squad, Exeter Chiefs coach Rob Baxter has backed Jack Nowell, Henry Slade and Luke Cowan-Dickie to be given a stay of execution.
Italy Under-20s held off a late Samoa blitz to retain their place in the World Rugby U20 Championship on Saturday and head coach Alessandro Troncon believes the experience will have served as a valuable lesson for his young troops.