With Bradley Davies suspended for the rest of the championships, head coach Warren Gatland made the call to shift Ospreys player from blindside to No. 4.
Jones has starred at lock for his club side but admits the position doesn't come naturally for him and he insists he will need to adjust quickly to fill the gap.
"I'm a little bit nervous about it," said Jones. "I have yet to figure at this level as a number four."
"It became a natural move having played some games at four this year for the Ospreys. It will be interesting to see how it goes but I'll go and give it my best shot.
"I've had bouts there, in and out and stuff, but I know what is required.
"There is a lot of difference really [between back-row and lock].
"It's all based around a tighter game and the other thing it doesn't come instinctively to me yet because I haven't played there regularly. I don't train there regularly.
"I'm looking forward to the challenge really and hopefully it will go well.
"We know they [Scotland] are going to be hurting and smarting from last weekend and coming down with a big point to prove."