"It's always a massive honour to play at Twickenham and as a team we have had some great experiences playing there, especially against New Zealand in the autumn," said the Darlington Mowden Park Sharks fly-half. "For us playing at a stadium like Twickenham doesn't add pressure, instead we thrive on the excitement and we will be doing our best to maintain our impressive record at the stadium."
England head into the clash against fierce rivals Wales on the back of wins over Scotland and Italy and the reigning Six Nations champions have only conceded three points on route to the third round.
"Obviously it's pleasing to have won two games from two so far as that is where we need to be to retain the Grand Slam but in terms of performances we have a lot to improve on," added McLean.
"We have definitely made too many individual errors and that is a big target for us to improve on going forward. The longer we retain the ball the harder it is for the opposition to do us damage and that's important in the games coming up against Wales, France and Ireland."
After consecutive championship wins since 2006, England are targeting a record seventh title but with Wales being the last side to defeat England in the championship, back in 2009 and in doing so denying Gary Street's side the Grand Slam, McLean knows that Saturday's clash will be their toughest challenge so far.
"Wales is always a tough game," said McLean. "They have always had a competitive pack and a back-row who want to compete at the breakdown and disrupt the way we play. They are coming to Twickenham and will be looking to cause an upset and we need to make sure that we are ready for that."
Rugby fans can watch the game for free with free entry to the stadium following the men's Six Nations match. The game is also live on the BBC Sport Red Button and on the BBC Sport website.
15 Natasha Hunt (Lichfield)
14 Kay Wilson (Bristol)
13 Emily Scarratt (Lichfield)
12 Rachael Burford (Richmond)
11 Michaela Staniford (Wasps)
10 Katy McLean (c) (Darlington Mowden Park Sharks)
9 La Toya Mason (Wasps)
1 Laura Keates (Worcester)
2 Victoria Fleetwood (Lichfield)
3 Sophie Hemming (Bristol)
4 Rowena Burnfield (Richmond)
5 Tamara Taylor(Darlington Mowden Park Sharks)
6 Hannah Gallagher (Saracens)
7 MarliePacker (Bristol)
8 Harriet Millar-Mils (Lichfield)
16 Amy Turner (Richmond)
17 Rochelle Clark (Worcester)
18 Margaret Alphonsi (Saracens)
19 SarahHunter (Lichfield)
20 Georgina Rozario (Lichfield)
21 Ceri Large (Worcester)
22 Kimberley Oliver (Bristol)
England's Six Nations Fixtures:
February 5th 2012, Scotland v England, Lasswade, Edinburgh, WON 47-0
February 12th 2012, Italy v England, Recco, Nr Genoa, WON 43-3
February 25th, 2012, England v Wales, Twickenham Stadium, KO 615pm
Live on the BBC Red Button and on www.bbc.co.uk/sport. Free entry to the stadium after the men's Six Nations match.
March 11th, 2012, France v England, Stade Charlety, Paris, KO 1245pm GMT
Live on Sky Sport HD2 Red Button.
March 17th2012 England v Ireland, Esher RFC, KO 2pm.
Live on www.rfu.com/englandwomenlive.com. Tickets can be purchased on game day on the gate or online at http://www.esherrugby.com/ticket_sales.html, priced £10 for adults, £5 for Under 16s.
Rugby Football Union for Women
+44 (0)7971 474557