Clive Woodward has vowed to take no notice of the RBS 6 Nations form guide which suggests tournament favourites England will give Wales a Millennium Stadium mauling on Saturday.
England, who have not lost in Cardiff since 1993, head for the Welsh capital later this week with 11 survivors in their starting line-up from last season's record 50-10 victory at Twickenham.
Wales are still feeling the after-effects from a 30-22 defeat by Italy, and Wales coach Steve Hansen's team selection - scheduled for Thursday - is likely to show several changes, including the possibility of him naming a new captain.
Woodward, though, is taking nothing for granted as England look to complete the second stage of a possible 6 Nations Grand Slam.
"In any of these 6 Nations games, and I speak from a lot of experience here, if you get anything wrong, then you will lose," he said.
"I am sure that Wales will think they have got a lot to prove, having lost their first game. If you lose your first game in the 6 Nations, then the second is a must-win.
"We are under no illusions that it is going to be a tough game on Saturday. There will be no problem with our guys in terms of focusing on the game.
"We've got a lot of experience about losing games in the championship that we should have won."
Scotland won three matches in this year's Championship
24 March 2017, 3:33pm
Scotland secured three RBS 6 Nations victories for the first time since 2006 as they beat Ireland, Wales and Italy at BT Murrayfield. Here we take a look at what lies ahead for the Scots in the next 12 months.
Peter Malone has been Nigel Carolan's assistant since 2015
24 March 2017, 11:56am
The IRFU have announced Peter Malone as the Ireland Under-20s interim head coach for the World Rugby Under-20 Championship in Georgia this summer after Nigel Carolan announced he would take a position at Guinness PRO12 side Connacht.