Edinburgh make two changes for the Leinster clash, with Argentine lock Esteban Lozada returning from a head injury in place of Craig Hamilton, and Ross Rennie replacing Netani Talei, with Roddy Grant switching to number eight.
Moffat is under no illusions as to the challenge facing his team against Leinster but maintains now is the time for his side to step up to the plate.
He said: "I am the first person to take responsibility and if we lose a game I think about what I can do better, and we're working to get that same message through the squad where we're all thinking about personal responsibility.
"What I don't want to do is stop players doing things because that's what can provide the difference between being successful on a field, opening teams up, and not. We don't want anyone going into their shell.
"We have to approach the Leinster game with both determination and confidence. It's our job this weekend to re-establish winning form on our own patch.
"We've done some good things in periods during all our games so far but we've also done a few basic things poorly."