The Official Online RBS 6 Nations Store is open. The store has everything you need to get behind your team during the RBS 6 Nations, plus the store is now fully stocked with a much wider range of rugby merchandise.
And former Red Dragon Dafydd Jones believes this most recent setback is another blow to the nation’s chances of repeating their 2012 success.
"We have got options but it isn't ideal we've lost three of our first choices and that's a big blow," he said.
"Luke Charteris is a big man. He's got so much to offer and is going to be a big loss.
"Obviously we've got Bradley Davies, we've got Ryan Jones also and young Lou Reed as well.
"They're [the Welsh selectors] going to be busy now over the Christmas period looking at who is in form and I wouldn't be surprised if someone had another chance."