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The Toulouse No.9 was withdrawn at half-time as an early George North try and the boot of Leigh Halfpenny established a 20-6 lead.
Sam Warburton added to the French misery after the break and brought their unbeaten start to the Championship to a shuddering halt.
And with clashes against Scotland and Ireland still to come, Doussain admits that he and his teammates have to take a long look in the mirror.
"It was difficult for me, for the team, for everyone," he said.
"We made it very easy for Wales and a team like that need no help, especially when they are at home.
"We gave them a try early on which set them up in the match and made it very complicated for us, we were up against from then on.
"We cannot say that we gave them the win because they certainly deserved it but it does not feel good to play a match like that."