The 93-cap back row scored Italy’s opening try of the tournament in the defeat of France but it appears he will be unavailable for Italy after being dismissed during the 30-14 defeat of Begles.

And Brunel, whose side were beaten by Scotland before the break, admits Parisse’s expected absence is a blow to his side’s ambitions.

“It is a huge set-back that is for sure, especially for him,” said Brunel.

“As coaches, it is just something we have to put up with. I have not spoken to Sergio yet. I don’t know the exact reason for this red card.”