Brian Carney will have a new chance to impress Ireland head coach Eddie O'Sullivan ahead of the World Cup.
The Munster player has been included in the tourists starting XV for the second Test against Argentina on Saturday.
The former rugby league player had a good performance in Saturdays 22-20 first Test defeat in Santa Fe, scoring.
And OSullivan said: I told him he played well (last Saturday), despite making a couple of mistakes.
I want to give him another chance to climb to the next level up.
Jeremy Staunton, who arrived in Buenos Aires in a hurry on Monday as replacement for the injured Paddy Wallace, will win his fifth cap in Buenos Aires.
Overall, there are 12 changes, including one positional, compared to the side which started last weekends match.
Geordan Murphy moves from the bench to start at full-back. Barry Murphy also comes into the starting side to partner Gavin Duffy, who will play at inside centre.
Paddy Wallace, Andrew Trimble and Tommy Bowe have been ruled out due to different injuries.
In the forwards, Frankie Sheahan replaces Jerry Flannery at hooker and the entire back five of the pack has been changed, with Leo Cullen and Mick ODriscoll in the second row.
Alan Quinlan and Stephen Ferris, who starts at number eight for his third cap, will join new cap Shane Jennings in the back row.