England captain Phil Vickery faces a crucial 48 hours in his bid to be fit for the RBS 6 Nations clash against France at Twickenham.
It has been confirmed that Vickery suffered concussion during Wasps' Premiership victory over Bristol on Sunday.
The 52 times-capped prop will be subject of an on-going medical review during the next 48 hours, while fly-half Jonny Wilkinson is due to undergo a scan on his right hamstring on Monday.
Lock Steve Borthwick, meanwhile, hopes to train on Wednesday as he battles a rib problem, but head coach Brian Ashton has called up three players into the England training squad.
Prop Stuart Turner and his Sale Sharks colleague Chris Jones, together with London Irish fly-half Shane Geraghty, will provide precautionary cover for Vickery, Borthwick and Wilkinson, respectively.
Elsewhere ahead of next Sunday's Test, centre Andy Farrell is receiving treatment for acute lower back pain at England's Bath University training base.
Centre Farrell, who is under pressure to retain his midfield place, missed Saracens' league win against Sale on Sunday.
A decision on his fitness will be made on Tuesday, but England say Farrell's former Wigan and Great Britain rugby league colleague Jason Robinson will then.
Wing Robinson, who has scored three tries during this season's RBS 6 Nations tournament, was ruled out of the Ireland Test after suffering a neck injury during training three days before the game.
He was replaced by Harlequins rookie David Strettle, another victim of the weekend's domestic action, although his "dead leg" injury sustained at Leicester is making good progress.
Vickery and Wilkinson though, will be the major concerns for Ashton as he ponders team selection to face France.
Vickery is currently going through the Rugby Football Union/Premier Rugby "concussion management protocol," and if he is ruled out, then it is likely that Leicester number eight Martin Corry would regain the captaincy he lost to Vickery two months ago.
Wilkinson, meanwhile, suffered a hamstring fitness scare ahead of the Ireland match, and he limped off late in Newcastle's Premiership defeat against London Irish two days ago.
Wilkinson's Newcastle colleague Toby Flood would be the obvious replacement, although uncapped Geraghty delivered an outstanding display against the Falcons - a game watched by Ashton.
Ashton is due to announce his starting line-up tomorrow morning, although the current injury situation suggests that could now be delayed.