Ireland coach Eddie O'Sullivan has named four uncapped players in his squad for the autumn Tests against New Zealand, Australia and Romania next month.
But Lions skipper Brian ODriscoll misses out, as expected, while he continues to recover from shoulder surgery.
ODriscoll is joined on the casualty list by Denis Hickie, Guy Easterby, Eric Miller and Alan Quinlan, while his fellow Lions Paul OConnell and Simon Easterby have been selected, subject to them undergoing fitness tests.
The four newcomers are Ulster flanker Neil Best, Leinsters 21-year-old number eight Jamie Heaslip, Leinster wing Robert Kearney, and Ulster centre Andrew Trimble.
OSullivan, meanwhile, has left a vacancy among the backs that will be filled after next weekends round of European Cup action.
The back-row is again an area where competition is high, said OSullivan. Both Jamie and Neil have impressed in their performances so far this season, and Andrew Trimble has slotted in well with Ulster and has also benefited from their good run.
Lock OConnell (hand) and flanker Easterby (broken nose) will face medical checks before deciding their availability, or otherwise.
OConnell was due to have a plaster-cast removed from his hand on Tuesday, while Easterby had surgery last weekend after being hurt during Llanelli Scarlets European Cup defeat against Toulouse.
Ireland launch their autumn campaign against the All Blacks in Dublin on November 12, followed by successive weekend appointments with Australia and Romania.
Ireland squad for autumn Tests against New Zealand, Australia and Romania:
Backs: T Bowe (Ulster), K Campbell (Ulster), G DArcy (Leinster), G Dempsey (Leinster), S Horgan (Leinster), D Humphreys (Ulster), R Kearney (Leinster), K Lewis (Leinster), G Murphy (Leicester), R OGara (Munster), D Quinlan (Northampton), P Stringer (Munster), A Trimble (Ulster), one player to be added.
Forwards: N Best (Ulster), S Best (Ulster), S Byrne (Saracens), R Corrigan (Leinster), L Cullen (Leicester), S Easterby (Llanelli Scarlets), A Foley (Munster), J Hayes (Munster), J Heaslip (Leinster), M Horan (Munster), M McCullough (Ulster), D Leamy (Munster), D OCallaghan (Munster), P OConnell (Munster), J OConnor (Wasps), M OKelly (Leinster), F Sheahan (Munster), D Wallace (Munster).