Ben Cohen fractured a cheekbone rather than his jaw in the Tsunami Aid match between the Northern Hemisphere and the Southern Hemisphere at Twickenham.
The England and Northampton winger is now waiting to discover how long he will be out of action.
It was initially thought that the injury was to his jaw, but the Northern Hemisphere press officer Louisa Cheetham confirmed otherwise.
Further medical treatment will be carried out on Sunday.
Cohen has not featured in this year's RBS 6 Nations but had been pencilled in for next weekend's clash with Italy in London, a match he is now sure to miss.
The 26-year-old would have featured on the wing, with Josh Lewsey moving to full-back in injured captain Jason Robinson's place, but now coach Andy Robinson must have a re-think.
Cohen, who has won 45 England caps and scored 29 tries, was a World Cup winner in 2003.
He was playing for the Northern Hemisphere side in Saturday's match to raise funds for victims of the Asian tsunami.
Robinson had selected him in a 30-man squad for the Italy game and Cohen was hoping for the chance to re-establish himself in the England side.
England have lost their opening three RBS 6 Nations matches but Robinson has been handicapped by the loss of several players through injury.
Mike Tindall, Will Greenwood, Jonny Wilkinson, Stuart Abbott, Phil Vickery, Julian White and Richard Hill are also currently sidelined.
Cohen is now understood to have returned to Northampton where he will see specialists to determine the length of his recovery period.