France centre Tony Marsh returns to the starting line-up for the Test match against Canada in Toronto on Saturday.
The New Zealand-born player missed Les Bleus 39-31 victory over the United States last weekend with a calf injury.
Meanwhile, Ludovic Loustau, Bernard Goutta, Arnaud Martinez and Philippe Bibabe will all make their international debuts on Saturday.
France struggled to overcome the Americans and were trailing 17-21 at the break before Mathieu Barrau and Thomas Lievremont led a second-half fightback.
Coach Bernard Laporte will be hoping for a better performance against the Canadians from the RBS 6 Nations champions.
France team: Clement Poitrenaud (Stade Toulousain), Philippe Bidabe (Biarritz), Tony Marsh (Montferrand), Brian Liebenberg (Stade Francais), Aurelien Rougerie (Montferrand), Alexandre Peclier (Bourgoin), Ludovic Loustau (Perpignan), Bernard Goutta (Perpignan), Thomas Lievremont (Biarritz), Yannick Nyanga (Beziers), Papé (Bourgoin), Fabien Pelous - captain (Stade Toulousain), Pieter De Villiers (Stade Francais), William Servat (Stade Toulousain), Arnaud Martinez (Narbonne).
Replacements: Dimitri Szarzewski (Beziers), Olivier Milloud (Bourgoin), David Couzinet (Biarritz), Pierre Rabadan (Stade Francais), Mathieu Barrau (Agen), Julien Peyrelongue (Biarritz), Cedric Heymans (Stade Toulousain).