Rob Dewey and Craig Hamilton are among the Scotland caps seeking to revitalise their international prospects in the opening match of the 2009 IRB Nations Cup against Russia in Bucharest.
Dewey, who has joined Glasgow from Ulster, starts on the wing with Edinburgh's Hamilton in the second row alongside Alastair Kellock in the Scotland A team.
There is no place in the starting line-up for Nick de Luca, though, with Alex Grove of Worcester preferred at centre alongside Ben Cairns.
De Luca played at the start of the 2009 RBS 6 Nations but was forced on the sidelines by the Glasgow combination of Graeme Morrison and Max Evans.
Now he cannot get in the 'A' side and has effectively become Scotland's fifth-choice centre, with Dewey another option in midfield.
Chris Cusiter leads the side from scrum-half with another Scotland squad regular Rory Lawson on the bench.
Test regular Simon Webster is on the other wing with Glasgow's promising stand-off Ruaridh Jackson receiving the No.10 shirt.
Andy Robinson, newly installed as Scotland head coach, leads the side and said: “Alex (Grove) has been given an opportunity to start in the back division and I¹ve liked what I¹ve seen of him so far.”