Ryan Jones has recovered from injury and will captain Wales in Saturday's RBS 6 Nations showdown against England at the Millennium Stadium.
But Wales head coach Warren Gatland still has two major fitness concerns in wing Shane Williams and number eight Andy Powell.
Jones is currently the only change from last weekend’s impressive 26-13 victory over Scotland in Edinburgh, replacing Dafydd Jones in the back row.
But Ospreys star Williams, who has scored 45 tries in 62 Tests, missed training today because of an ankle injury suffered at Murrayfield.
Powell pulled up in training today with a tight calf muscle and Wales’ fitness staff will give the injury time to settle before making a proper assessment.
If Williams is ruled out - he will be reassessed tomorrow after further rest - then Scarlets wing Mark Jones will be promoted from outside the match-day 22 to win his 44th cap after recovering from appendix surgery.
Centre Gavin Henson, meanwhile, has not sufficiently recovered from a calf strain to be made available for selection.
Henson was originally selected to face Scotland, but withdrew barely 48 hours before kick-off.
He now misses an eighth successive Test match, although it would have been a huge call by Gatland to change the all-Cardiff Blues midfield partnership of Tom Shanklin and Jamie Roberts, given their superb Murrayfield displays.
The possible loss of Williams, Powell or both would rock Welsh hopes of a third successive RBS 6 Nations victory against England.
Should Powell not make it, Gatland looks likely to move Ryan Jones to number eight, then recall Dafydd Jones off the bench and retain the number six shirt he wore against Scotland.
Wales were surprise victors over England at Twickenham last season, but a year on they find themselves installed as red-hot favourites - a fact not lost on Gatland.
He said: “The fixture is a bit of a reversal from last year.
“It just shows that a lot of things can change in 12 months, but there is also a lesson there in that we were not tipped to win at Twickenham, but we did and it sparked our season.
“We will need to play better all around the park than we did last week if we are to beat England.
“They are a side with a vast amount of experience and they will respond well to having their backs to the wall.
“We have reached fourth place in the International Rugby Board world rankings, and our challenge now is to stay there and maintain consistency of performance.”
Wales team to play England in the RBS 6 Nations Championship at the Millennium Stadium, Saturday, February 14, 1730:
L Byrne (Ospreys); L Halfpenny (Cardiff Blues), T Shanklin (Cardiff Blues), J Roberts (Cardiff Blues), S Williams (Ospreys); S Jones (Scarlets), M Phillips (Ospreys); G Jenkins (Cardiff Blues), M Rees (Scarlets), A Jones (Ospreys), I Gough (Ospreys), A-W Jones (Ospreys), R Jones (Ospreys, capt), M Williams (Cardiff Blues), A Powell (Cardiff Blues).
H Bennett (Ospreys), J Yapp (Cardiff Blues), L Charteris (Newport Gwent Dragons), D Jones (Scarlets), D Peel (Sale Sharks), J Hook (Ospreys), A Bishop (Ospreys).