A year after Warren Gatland's team turned the form book upside down by toppling England at Twickenham, the bookmakers have no doubt they will repeat the result in Cardiff.

And it is hard to disagree following an opening weekend of Six Nations action when Wales roared to a four-try victory over Scotland at Murrayfield, while England toiled painfully before despatching Italy 36-11.

Wales are seeking a first hat-trick of RBS 6 Nations wins against England, and a seventh tournament win in succession against all opponents.

Also to underline England's degree of difficulty, Wales have not lost an RBS 6 Nations home game since Ireland beat them in February 2007.

England boss Martin Johnson's team selection suggests his team will look to dominate Wales up-front, hoping that prop Andrew Sheridan can rediscover his most destructive scrummaging form and locks Steve Borthwick and Nick Kennedy can take charge against a sometimes suspect Welsh lineout.

In all other areas, though, England look destined to struggle.

Wales positively bristle with pace and panache behind the scrum, and they will want their strike-runners to make maximum gain from the presence of midfield wrecking ball Jamie Roberts.

The Cardiff Blues powerhouse scattered Scottish defenders to all parts in Edinburgh last Sunday, and while England might know what's coming, stopping it is an altogether different business.

Wales showed in Scotland they are comfortable coping with the expectation surrounding them, and with momentum already rolling, it is hard to imagine the red machine stalling on Saturday.