The Official Online RBS 6 Nations Store is open. The store has everything you need to get behind your team during the RBS 6 Nations, plus the store is now fully stocked with a much wider range of rugby merchandise.
Henson's injury will be reassessed next week ahead of Wales' Millennium Stadium appointment with England in eight days' time.
It is the second occasion this season Wales head coach Warren Gatland has seen his hopes of fielding a Henson-Roberts midfield combination dashed.
Gatland had hoped to do it against world champions South Africa in November, but Henson pulled out 24 hours before kick-off due to an Achilles' problem, which followed an ankle injury that sidelined him post-Six Nations last year.
Henson now misses his seventh successive Test match, with a possible bad omen looming for Wales this weekend in that they have never lost a Six Nations game he has started.
Shanklin though, is a high-class replacement who will win his 59th cap on Sunday, and Bishop moves on to the bench following a series of impressive Heineken Cup and Magners League displays for the Ospreys.
The Wales squad fly to Edinburgh later today, having beaten Scotland just twice at Murrayfield since 1985.