Goode, 28, starts at fly-half after England boss Martin Johnson demoted Danny Cipriani to the Saxons while Toby Flood has been struggling with a calf injury.

England’s starting XV features five changes from the November defeat to New Zealand and includes a debut for London Irish flanker Steffon Armitage, who has been promoted straight into the team following injuries to Tom Rees, Lewis Moody and Michael Lipman.

Steffon Armitage and full-back Delon Armitage will become the first brothers to play in the same England team since the Underwoods, Rory and Tony, in 1995.

Mike Tindall returns at outside centre with Mark Cueto back on the wing for the first time since the 2007 World Cup final to replace the injured Ugo Monye, while Andrew Sheridan returns at loose-head.

Northampton’s versatile back Ben Foden is poised to make his debut off the bench, where he features alongside veteran Leicester prop Julian White who replaced Matt Stevens in the elite squad.

Goode last appeared for England in the 2006 November defeat to South Africa - Andy Robinson’s last game in charge - but returns to the international stage in prime form.

Having swapped Leicester for Brive during the summer, Goode is the leading points scorer in the French Top 14.

Goode joined the England squad for last week’s training camp in Portugal and his inclusion will see the fly-half jersey change hands for the sixth time in eight Tests.

Cipriani was yesterday dropped to the Saxons squad for Friday night’s game against Ireland A in Dublin.

England team to play Italy in the RBS 6 Nations at Twickenham on Saturday, February 7, kick-off 3pm:

D Armitage (London Irish); P Sackey (Wasps), M Tindall (Gloucester), R Flutey (Wasps), M Cueto (Sale Sharks); A Goode (Brive), D Care (Harlequins); A Sheridan (Sale Sharks), L Mears (Bath), P Vickery (Wasps), S Borthwick (Saracens, capt), N Kennedy (London Irish), J Haskell (Wasps), S Armitage (London Irish), N Easter (Harlequins).

Replacements: D Hartley (Northampton), J White (Leicester), T Croft (Leicester), J Worsley (Wasps), B Foden (Northampton), S Geraghty (London Irish), M Tait (Sale Sharks).