Martin Johnson has included four debutants - Delon Armitage, Ugo Monye, Riki Flutey and Nick Kennedy - in the England team to start against the Pacific Islanders on Saturday.
Johnson’s first squad selection as the England team boss also includes a potential fifth debutant in Dylan Hartley, the uncapped Northampton hooker who has been included on the bench.
Kennedy, the London Irish lock, toured with England to New Zealand in the summer but did not feature in either Test defeat.
He will start in the second row alongside captain Steve Borthwick after being preferred to Wasps duo Tom Palmer and Simon Shaw.
Armitage will start at full-back with Monye, who has been in electric form for Harlequins this season, on the left wing and Flutey at inside centre.
Flutey, the former Junior All Black and New Zealand Maori, qualified to play for England on residency grounds in September and he has been promoted straight into the team.
Jamie Noon will start on Flutey’s right shoulder at outside centre, while Danny Cipriani and Danny Care link up in the half-backs.
Up front, Harlequins’ Nick Easter has returned to the side at number eight with dynamic Leicester flanker Tom Croft preferred to James Haskell on the blindside.
In the front row, Bath tight-head prop Matt Stevens has kept out former captain Phil Vickery while Lee Mears retained the hooker’s jersey despite competition from Hartley.
D Armitage (London Irish); P Sackey (Wasps), J Noon (Newcastle), R Flutey (Wasps), U Monye (Harlequins); D Cipriani (Wasps), D Care (Harlequins); A Sheridan (Sale Sharks), L Mears (Bath), M Stevens (Bath), S Borthwick (Saracens, captain), N Kennedy (London Irish), T Croft (Leicester), T Rees (Wasps), N Easter (Harlequins).
D Hartley (Northampton), P Vickery (Wasps), T Palmer (Wasps), J Haskell (Wasps), M Lipman (Bath), H Ellis (Leicester), T Flood (Leicester).