Ireland A skipper Bob Casey returns to London Irish's match-day squad against Harlequins at the Twickenham Stoop tomorrow.
Exiles club captain Casey is among the replacements after breaking his wrist against pre-season opponents Munster last month.
Irish head coach Toby Booth said: “The game provides us with a chance to keep up with the early pace-setters in the Premiership.
“Having started so well on the opening weekend (Irish beat Wasps), we are disappointed to have missed out on maximum points, albeit narrowly, over the past fortnight.
“Quins have had a great start to their season, which comes as no surprise to us, having played a tough pre-season match against them last month.”